Notation:
- sensitivity: \(s\)
- specificity: \(c\)
- PPV: \(p\)
- prevalence: \( \rho \)
- NPV: \( \nu\)
AUC
PPV
PPV is the fraction of true positives to all positive flags, i.e.,
$ p = \frac{t_p}{t_p+f_p} $
From sensitivity and specificity, PPV may be calculated as follows:
PPV = (sensitivity x prevalence) / [ (sensitivity x prevalence) + ((1 – specificity) x (1 – prevalence)) ]
$ p = \frac{s \rho}{s \rho + (1-c)(1-\rho)} $
NPV
NPV is the fraction of true negatives in all negative flags, i.e.,
$ \nu = \frac{t_n}{t_n+f_n} $
From sensitivity and specificity, we can calculate:
NPV = (specificity x (1 – prevalence)) / [ (specificity x (1 – prevalence)) + ((1 – sensitivity) x prevalence) ]
$ \nu = \frac{c(1-\rho)}{c(1-\rho) + (1-s)\rho} $
